WebRNF38, the ring finger protein 38, belongs to one of the largest E3 ubiquitin ligase family proteins. 7 RNF38 protein contains RING-H2 domain, KIL domain and coiled-coil domain at its carboxyl end. 7 Among them, RING zinc finger motifs are zinc-binding domains in RNF ubiquitin ligase family proteins, which can promote the transfer of … WebMyc proteins act as master regulators of two very dis-tinct genetic programs: On the one hand, they stimulate virtually all nuclear processes leading to enhanced cell growth (the accumulation of cell mass); on the other hand, Myc proteins cancel the cell cycle arrest induced by multiple growth-inhibitory pathways. Both these ac-
Entry - *600382 - MYC PROMOTER-BINDING PROTEIN - OMIM
WebPlots were binned by Myc protein levels after siMyc and exogenous expression of an siRNA-resistant, intron-less Myc. Endogenous Myc protein range determined in separate, unperturbed wells. Fluorescence of biological replicates adjusted to account for experiment-to-experiment variability in arbitrary fluorescence values. WebHerein, we identified and explored a novel multiple myeloma target: the fatty acid binding protein (FABP) family. In our work, myeloma cells were treated with FABP inhibitors (BMS3094013 and SBFI-26) and examined in vivo and in vitro for cell cycle state, proliferation, apoptosis, mitochondrial membrane potential, cellular metabolism (oxygen … royalview mtb
Recombinant Human TEAD4 Protein (74-434), N-10×His and C-Myc …
Web9 apr. 2024 · Deregulated protein synthesis is a common feature of cancer cells, with many oncogenic signaling pathways directly augmenting protein translation to support the … WebFOXA1 has also been identified as one of the seven molecular subtypes of primary prostate cancer. In the present study, we used an efficient gene knock-out method, CRISPR/Cas9, in order to investigate FOXA1 function on LNCaP prostate cancer cells in vitro. FOXA1 knock-out altered cell-cycle regulator CCND1 protein expression levels. WebThe Brucella effector protein TcpB induces degradation of inflammatory caspases and thereby subverts non-canonical inflammasome ... which is a potent inducer of the non-canonical inflammasome pathway. ... HEK293T cells were cotransfected with various combinations of MYC-TcpB, FLAG-caspases, and HA-ubiquitin as indicated. 24 h post ... royalview splendour